Margaret Karpatkin, M.D.
Publications
| 1. | Schwartz, N; Oldenburg, J; Hart, D; Nardi, M; Most, OL; Bonanno, C; Timor-Tritsch, IT; Karpatkin, M. "Intrauterine subdural hemorrhage associated with profound deficiency of the vitamin K dependent clotting factors in an infant homozygous for a common polymorphism in the vitamin K epoxide reductase complex 1 (VKORC1) promoter [Abstract]". Blood. 2007; 110: 640A (#J0134210) |
| 2. | Karpatkin, S; Karpatkin, M. "Marjorie Zucker, PhD, 1919-2006 - Obituary". Journal of thrombosis & haemostasis : JTH. 2006; 4: 1847 (#J0118403) |
| 3. | Zhu, CC; Karpatkin, M; Carpov, A; Nardi, MA. "Lupus anticoagulant testing: Are "lupus sensitive" reagents and addition of excess phospholipid always necessary? [Abstract]". Blood. 2005; 106: 606A (#J0110594) |
| 4. | Nadziejko C; Fang K; Chen LC; Cohen B; Karpatkin M; Nadas A. "Effect of concentrated ambient particulate matter on blood coagulation parameters in rats". Research report (Health Effects Institute). 2002; 3: 7 (#J0048172) |
| 5. | Rogoff EG; Guirguis HS; Lipton RA; Seremetis SV; DiMichele DM; Agnew GM; Karpatkin M; Barish RJ; Jones RL; Bianco C; Knothe BD; Lee MS. "The upward spiral of drug costs: a time series analysis of drugs used in the treatment of hemophilia [Comment]". Thrombosis & haemostasis. 2002; 88: 545 (#J0048173) |
| 6. | Dhodapkar K; Corbacioglu S; Chang MW; Karpatkin M; DiMichele D. "Purpura fulminans caused by group A beta-hemolytic Streptococcus sepsis". Journal of pediatrics. 2000; 137: 562 (#J0018025) |
| 7. | Karpatkin M; Lee M; Cohen L; McKinnell J; Nardi M. "Synthesis of coagulation proteins in the fetus and neonate". Journal of pediatric hematology/oncology. 2000; 22: 276 (#J0008873) |
| 8. | Karpatkin M. "Coagulation problems in the newborn". Seminars in neonatology. 1999; 4: 67 (#J0017554) |
| 9. | Oddoux C; Guillen-Navarro E; Ditivoli C; Dicave E; Cilio MR; Clayton CM; Nelson H; Sarafoglou K; McCain N; Peretz H; Seligsohn U; Luzzatto L; Nafa K; Nardi M; Karpatkin M; Aksentijevich I; Kastner D; Axelrod F; Ostrer H . "Mendelian diseases among Roman Jews: implications for the origins of disease alleles". Journal of clinical endocrinology & metabolism. 1999; 84: 4405 (#J0004234) |
| 10. | Samuel H; Nardi M; Karpatkin M; Hart D ; Belmont M; Karpatkin S. "Differentiation of autoimmune thrombocytopenia from thrombocytopenia associated with immune complex disease: systemic lupus erythematosus, hepatitis-cirrhosis, and HIV-1 infection by platelet and serum immunological measurements". British journal of haematology. 1999; 105: 1086 (#J0000438) |
| 11. | Landesberg R; Moses M; Karpatkin M. "Risks of using platelet rich plasma gel [Letter]". Journal of oral & maxillofacial surgery. 1998; 56: 1116 (#J0048174) |
| 12. | Cohen L; McKinnell J; Puglisi V; Greco A; Nardi M; Lee M; Karpatkin M. "Prothrombin synthesis in the adult and fetal liver". Thrombosis & haemostasis. 1997; 78: 1468 (#J0009724) |
| 13. | Oddoux, C; Guillen-Navarro, E; Clayton, CM; Nelson, H; Peretz, H; Seligsohn, U; Luzzatto, L; Nardi, M; Karpatkin, M; DiTivoli, C; DiCave, E; Axelrod, F; Ostrer, H. "Genetic evidence for a common origin among Roman Jews and Ashkenazi Jews [Abstract]". American journal of human genetics. 1997; 61: A207 (#J0094888) |
| 14. | Wistinghausen B; Reischer A; Oddoux C; Ostrer H; Nardi M; Karpatkin M. "Severe factor XI deficiency in an Arab family associated with a novel mutation in exon 11". British journal of haematology. 1997; 99: 575 (#J0009755) |
| 15. | Choe EI; Kasabian AK; Kolker AR; Karp NS; Zhang L; Bass LS; Nardi M; Josephson G; Karpatkin M. "Thrombocytosis after major lower extremity trauma: mechanism and possible role in free flap failure". Annals of plastic surgery. 1996; 36: 489 (#J0010365) |
| 16. | Lee MT; Nardi MA; Hadzi-Nesic J; Karpatkin M. "Transient hemorrhagic diathesis associated with an inhibitor of prothrombin with lupus anticoagulant in a 1 1/2-year-old girl: report of a case and review of the literature". American journal of hematology. 1996; 51: 307 (#J0001838) |
| 17. | Wistinghausen, B; Nardi, M; Karpatkin, M. "Factor XI deficiency in an Arab family not due to the common type II or III mutations [Abstract]". Pediatric research. 1996; 39: 968 (#J0092951) |
| 18. | Wistinghausen, B; Reischer, A; Nardi, M; Karpatkin, M. "Severe factor XI deficiency in an Arab family associated with a novel mutation in exon 11 [Abstract]". Blood. 1996; 88: 3012 (#J0092115) |
| 19. | Flug F; Karpatkin M; Karpatkin S. "Should all pregnant women be tested for their platelet PLA (Zw, HPA-1) phenotype?". British journal of haematology. 1994; 86: 1 (#J0104069) |
| 20. | LEE, M; NARDI, MA; HU, G; HADZINESIC, J; KARPATKIN, M. "TRANSIENT INHIBITOR OF PROTHROMBIN IN A 1-1/2 YEAR-OLD GIRL, PROBABLY DIRECTED AGAINST THE F1.2 PORTION OF THE MOLECULE [Abstract]". Pediatric research. 1994; 35: A164 (#J0091412) |
| 21. | KARPATKIN, M; COHEN, L; TANG, ZC; NARDI, M. "PLASMA PROTHROMBIN LEVELS IN THE FETAL RABBIT DO NOT REFLECT RATE OF SYNTHESIS [Abstract]". Clinical research. 1993; 41: A314 (#J0097052) |
| 22. | LEE, M; TEPERMAN, L; GOLDENBERG, A; KARPATKIN, M. "PROLONGED ABNORMALITIES OF HEMOSTASIS FOLLOWING ORTHOTOPIC LIVER-TRANSPLANTATION [Abstract]". Blood. 1993; 82: A596 (#J0090221) |
| 23. | Ankola P; Nardi M; Karpatkin M. "Functional activity of protein C in newborn infants. A report of a study and a review of the literature". American journal of pediatric hematology-oncology. 1992; 14: 140 (#J0004321) |
| 24. | Rigaud M; Leibovitz E; Quee CS; Kaul A; Nardi M; Pollack H; Lawrence R; DiJohn D; Krasinski K; Karpatkin M; et al. "Thrombocytopenia in children infected with human immunodeficiency virus: long-term follow-up and therapeutic considerations". Journal of acquired immune deficiency syndromes. JAIDS. 1992; 5: 450 (#J0012270) |
| 25. | Karpatkin M; Tang ZC; Meer J; Blei F; Samuels HH. "Cloning and partial sequence of a cDNA for rabbit prothrombin". Thrombosis research. 1991; 62: 757 (#J0012667) |
| 26. | Karpatkin M; Blei F; Hurlet A; Greco A; Tang Z. "Prothrombin expression in the adult and fetal rabbit liver". Pediatric research. 1991; 30: 266 (#J0105020) |
| 27. | KARPATKIN, M; TANG, Z; PUGLISI, V; HURLET, A; BLEI, F. "PROTHROMBIN SYNTHESIS IN THE ADULT AND FETUS - STUDIES IN A RABBIT MODEL [Abstract]". Pediatric research. 1991; 29: A143 (#J0088629) |
| 28. | RIGAUD, M; LEIBOVITZ, E; SINQUEE, C; KAUL, A; NARDI, M; POLLACK, H; LAWRENCE, R; DIJOHN, D; KRASINSKI, K; KARPATKIN, M; BORKOWSKY, W. "THROMBOCYTOPENIA IN CHILDREN INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) - LONG-TERM FOLLOW-UP AND THERAPEUTIC CONSIDERATIONS [Abstract]". Pediatric research. 1991; 29: A182 (#J0088636) |
| 29. | Sthoeger D; Nardi M; Travis S; Karpatkin M; Karpatkin S. "Micromethod for demonstrating increased platelet surface immunoglobulin G: findings in acute, chronic, and human immunodeficiency virus-1-related immunologic thrombocytopenias". American journal of hematology. 1990; 34: 275 (#J0013798) |
| 30. | Weinberg, RS; Giardina, PJ; Karpatkin, M; Alter, BP. "CHARACTERISTICS OF ERYTHROID PROGENITOR CELLS IN BETA- THALASSEMIA MAJOR (TM) AND BETA-THALASSEMIA INTERMEDIA (TI) [Abstract]". Pediatric research. 1990; 27: A152 (#J0043338) |
| 31. | Sthoeger D; Nardi M; Karpatkin M. "Protein S in the first year of life". British journal of haematology. 1989; 72: 424 (#J0007167) |
| 32. | Hart, D; Nardi, M; Porges, RF; Karpatkin, M. "THROMBOCYTOPENIA DURING PREGNANCY". New England journal of medicine. 1988; 319: 1483 (#J0040884) |
| 33. | Karpatkin S; Finlay TH; Ballesteros AL; Karpatkin M. "Effect of warfarin on prothrombin synthesis and secretion in human Hep G2 cells". Blood. 1987; 70: 773 (#J0013805) |
| 34. | ANKOLA, P; NARDI, MA; KARPATKIN, M. "PROTEIN-C IN NEWBORN-INFANTS HAS LOWER FUNCTIONAL-ACTIVITY THAN IN ADULTS [abstract]". Pediatric research. 1986; 20: A387 (#J0062961) |
| 35. | Hart D; Dunetz C; Nardi M; Porges RF; Weiss A; Karpatkin M. "An epidemic of maternal thrombocytopenia associated with elevated antiplatelet antibody. Platelet count and antiplatelet antibody in 116 consecutive pregnancies: relationship to neonatal platelet count". American journal of obstetrics & gynecology. 1986; 154: 878 (#J0048175) |
| 36. | Karpatkin M; Mannuccio Mannucci P; Bhogal M; Vigano S; Nardi M. "Low protein C in the neonatal period". British journal of haematology. 1986; 62: 137 (#J0048176) |
| 37. | Karpatkin, S; Finlay, T; Ballesteros, A; Karpatkin, M. "REGULATION OF PROTHROMBIN SYNTHESIS IN HUMAN HEP-G2 CELLS - FEEDBACK INHIBITION BY EXOGENOUS PROTHROMBIN - COUMADIN INHIBITS SECRETION BUT NOT SYNTHESIS [Abstract]". Clinical research. 1986; 34: A659 (#J0040097) |
| 38. | NARDI, MA; KARPATKIN, M. "PROTEIN-C AND PROTHROMBIN DO NOT REACH MEAN ADULT LEVELS UNTIL THE 4TH YEAR OF LIFE [abstract]". Pediatric research. 1986; 20: A392 (#J0062962) |
| 39. | Nardi M; Karpatkin M. "Prothrombin and protein C in early childhood: normal adult levels are not achieved until the fourth year of life". Journal of pediatrics. 1986; 109: 843 (#J0004319) |
| 40. | Karpatkin M; Karpatkin S. "Regulation of blood coagulation factor levels in plasma". Current topics in hematology. 1985; 5: 113 (#J0013814) |
| 41. | Karpatkin, M. "STEROID-THERAPY OF NEONATAL ITP - REPLY". Journal of pediatrics. 1985; 107: 157 (#J0039828) |
| 42. | Piomelli S; Hart D; Graziano J; Grant G; Karpatkin M; McCarthy K. "Current strategies in the management of Cooley's anemia". Annals of the New York Academy of Sciences. 1985; 445: 256 (#J0048177) |
| 43. | Karpatkin M. "Corticosteroid therapy in thrombocytopenic infants of women with autoimmune thrombocytopenia". Journal of pediatrics. 1984; 105: 623 (#J0048178) |
| 44. | KARPATKIN, M; HOWARD, L; KARPATKIN, S. "STUDIES ON THE ORIGIN OF PLATELET-ASSOCIATED FIBRINOGEN - GLANZMANNS THROMBASTHENIC PLATELETS CONTAIN NEAR NORMAL FIBRINOGEN [Abstract]". Clinical research. 1984; 32: A497 (#J0060819) |
| 45. | Karpatkin M; Howard L; Karpatkin S. "Studies of the origin of platelet-associated fibrinogen". Journal of laboratory & clinical medicine. 1984; 104: 223 (#J0013818) |
| 46. | Andrew M; Manno M; Karpatkin M. "Demonstration of kallikrein-like protease activity in nonactivated plasma of patients with Cooley's anemia". Blood. 1983; 61: 232 (#J0048180) |
| 47. | Andrew M; Massicotte-Nolan PM; Karpatkin M. "Plasma protease inhibitors in premature infants: influence of gestational age, postnatal age, and health status". Proceedings of the Society for Experimental Biology & Medicine. 1983; 173: 495 (#J0048179) |
| 48. | Karpatkin S; Chang RJ; Pierce W; Karpatkin M. "Effect of coumadin-induced coagulopoietin plasma on vitamin K-dependent carboxylation of liver microsomes". British journal of haematology. 1983; 55: 673 (#J0013822) |
| 49. | Andrew, M; Karpatkin, M. "A NEW KALLIKREIN-LIKE PROTEASE IN PLASMA OF PATIENTS WITH COOLEY ANEMIA ASSOCIATED WITH LOW-LEVELS OF CONTACT FACTORS [Abstract]". Clinical research. 1982; 30: A558 (#J0038895) |
| 50. | Andrew M; Karpatkin M. "A simple screening test for evaluating prolonged partial thromboplastin times in newborn infants". Journal of pediatrics. 1982; 101: 610 (#J0048181) |
| 51. | Karpatkin, M; Porges, RF; Karpatkin, S. "STEROID-ADMINISTRATION IN PREGNANT-WOMEN WITH AUTOIMMUNE THROMBOCYTOPENIA - REPLY". New England journal of medicine. 1982; 306: 745 (#J0038745) |
| 52. | Andrew M; Bhogal M; Karpatkin M. "Factors XI and XII and prekallikrein in sick and healthy premature infants". New England journal of medicine. 1981; 305: 1130 (#J0048182) |
| 53. | ANDREW, M; BHOGAL, M; KARPATKIN, M. "POOR CLINICAL STATUS IMPAIRS THE POSTNATAL RISE OF THE CONTACT FACTORS IN PREMATURE-INFANTS". Pediatric research. 1981; 15: 572 (#J0058390) |
| 54. | ANDREW, M; MANNO, M; KARPATKIN, M. "PRESENCE OF A SERINE PROTEASE IN UNACTIVATED PLASMA OF CHILDREN WITH COOLEYS ANEMIA". Pediatric research. 1981; 15: 573 (#J0058391) |
| 55. | Andrew, M; Manno, M; Karpatkin, M. "UNACTIVATED PLASMA OF CHILDREN WITH COOLEYS ANEMIA HAS SERINE PROTEASE ACTIVITY [Abstract]". Thrombosis & haemostasis. 1981; 46: 229 (#J0038091) |
| 56. | Graziano JH; Piomelli S; Hilgartner M; Giardina P; Karpatkin M; Andrew M; LoIacono N; Seaman C. "Chelation therapy in beta-thalassemia major. III. The role of splenectomy in achieving iron balance". Journal of pediatrics. 1981; 99: 695 (#J0048183) |
| 57. | Karpatkin M; Karpatkin S. "Humoral substances regulating the levels of coagulation factors: coagulopoietins". Annals of the New York Academy of Sciences. 1981; 370: 281 (#J0013839) |
| 58. | Karpatkin M; Karpatkin S. "Immune thrombocytopenia in children". American journal of pediatric hematology-oncology. 1981; 3: 213 (#J0013838) |
| 59. | Karpatkin M; Porges RF; Karpatkin S. "Platelet counts in infants of women with autoimmune thrombocytopenia: effects of steroid administration to the mother". New England journal of medicine. 1981; 305: 936 (#J0013836) |
| 60. | Mitnick JS; Bosniak MA; Megibow AJ; Karpatkin M; Feiner HD; Kutin N; Van Natta F; Piomelli S. "CT in B-thalassemia: iron deposition in the liver, spleen, and lymph nodes". American journal of roentgenology. 1981; 136: 1191 (#J0048184) |
| 61. | Andrew, M; Bhogal, M; Ganapathy, S; Karpatkin, M. "INITIAL-STAGES OF BLOOD-COAGULATION IN PREMATURE-INFANTS [Abstract]". Pediatric research. 1980; 14: 530 (#J0032039) |
| 62. | Karpatkin M. "Screening tests in hemostasis". Pediatric clinics of North America. 1980; 27: 831 (#J0048185) |
| 63. | Mehta P; Vasa R; Neumann L; Karpatkin M. "Thrombocytopenia in the high-risk infant". Journal of pediatrics. 1980; 97: 791 (#J0048186) |
| 64. | Piomelli S; Graziano J; Karpatkin M; Dudell GG; Hart D; Hilgartner M; Khanna K; Valdes-Cruz LM; Vora S. "Chelation therapy, transfusion requirement, and iron balance in young thalassemic patients". Annals of the New York Academy of Sciences. 1980; 344: 409 (#J0048187) |
| 65. | Karpatkin M; Karpatkin S. "Humoral factor that specifically regulates prothrombin (factor II) levels (coagulopoietin-II)". Proceedings of the National Academy of Sciences of the United States of America. 1979; 76: 491 (#J0013854) |
| 66. | Trauber D; Hawkins K; Karpatkin M; Karpatkin S. "Humoral factor that specifically regulates factor X levels in rabbits (coagulopoietin-X)". Journal of clinical investigation. 1979; 64: 1713 (#J0013849) |
| 67. | Gershon AA; Piomelli S; Karpatkin M; Smithwick E; Steinberg S. "Antibody to varicella-zoster virus after passive immunization against chickenpox". Journal of clinical microbiology. 1978; 8: 733 (#J0048188) |
| 68. | Karpatkin, M. "FACTOR-XI AND FACTOR-XII IN CRITICALLY ILL NEONATES [Abstract]". Pediatric research. 1978; 12: 466 (#J0036876) |
| 69. | Karpatkin S; Karpatkin M; Altszuler H. "Identification of a coagulopoietin for prothrombin". Transactions of the Association of American Physicians. 1978; 91: 351 (#J0013860) |
| 70. | KARPATKIN, S; KARPATKIN, M. "INVITRO AND INVIVO IDENTIFICATION OF A COAGULOPOIETIN FOR PROTHROMBIN [Abstract]". Clinical research. 1978; 26: A554 (#J0169667) |
| 71. | Weiner M; Karpatkin M; Hart D; Seaman C; Vora SK; Henry WL; Piomelli S. "Cooley anemia: high transfusion regimen and chelation therapy, results, and perspective". Journal of pediatrics. 1978; 92: 653 (#J0048189) |
| 72. | Karpatkin, M; Altszuler, H; Karpatkin, S. "COAGULOPOIETIN-PROTHROMBIN - SPECIFIC HUMORAL FACTOR [Abstract]". Blood. 1977; 50: 272 (#J0035989) |
| 73. | Karpatkin M; Siskind GW; Karpatkin S. "The platelet factor 3 immunoinjury technique re-evaluated. Development of a rapid test for antiplatelet antibody. Detection in various clinical disorders, including immunologic drug-induced and neonatal thrombocytopenias". Journal of laboratory & clinical medicine. 1977; 89: 400 (#J0013866) |
| 74. | Vasa, R; Smedresman, P; Perlman, R; Karpatkin, M; Neumann, LL. "EXPERIENCE WITH NEONATAL THROMBOCYTOPENIA [Abstract]". Pediatric research. 1977; 11: 544 (#J0036078) |
| 75. | Weiner, M; Karpatkin, M; Hart, D; Seaman, C; Vora, S; Piomelli, S. "COOLEYS ANEMIA - TRANSFUSIONS REGIMEN AND IRON BALANCE [Abstract]". Pediatric research. 1977; 11: 483 (#J0036074) |
| 76. | Friedman EW; Karpatkin M; Karpatkin S. "Evidence suggesting the regulation of a coagulation factor levels in rabbits by a transferable plasma agent". Blood. 1976; 48: 949 (#J0013868) |
| 77. | Karpatkin S; Karpatkin M. "Inhibition of the enzymatic activity of thrombin by concanavalin A". Biochemical & biophysical research communications. 1974; 57: 1111 (#J0013883) |
| 78. | Piomelli S; Karpatkin MH; Arzanian M; Zamani M; Becker MH; Geneiser N; Danoff SJ; Kuhns WJ. "Hypertransfusion regimen in patients with Cooley's anemia". Annals of the New York Academy of Sciences. 1974; 232: 186 (#J0035232) |
| 79. | Karpatkin M; Karpatkin S. "Evidence for a humoral agent capable of raising vitamin-K-dependent coagulation factors in rabbits". British journal of haematology. 1973; 24: 553 (#J0013888) |
| 80. | Karpatkin M; Sacker I; Ackerman N. "Respiratory-distress syndrome and disseminated intravascular coagulation in two siblings". Lancet. 1972; 1: 102 (#J0048191) |
| 81. | Mehta B; Briggs DK; Sommers SC; Karpatkin M. "Disseminated intravascular coagulation following cardiac arrest: a study of 15 patients". American journal of the medical sciences. 1972; 264: 353 (#J0048190) |
| 82. | Johnson AJ; Karpatkin MH; Newman J. "[Clinical investigation of intermediate- and high-purity antihaemophilic factor (factor VIII) concentrates.]". British journal of haematology. 1971; 21: 21 (#J0035234) |
| 83. | Newman J; Johnson AJ; Karpatkin MH; Puszkin S. "Methods for the production of clinically effective intermediate- and high-purity factor-VIII concentrates". British journal of haematology. 1971; 21: 1 (#J0035233) |
| 84. | Johnson AJ; Karpatkin MH; Newman J. "Purification and clinical evaluation of a factor 8 concentrate". Bibliotheca haematologica. 1970; 34: 30 (#J0035235) |
| 85. | Karpatkin M. "Fibrin split products in serum of newborn: possible technical errors". Pediatrics. 1970; 45: 157 (#J0048192) |
| 86. | Karpatkin MH; Karpatkin S. "In vivo and in vitro binding of factor VIII to human platelets". Thrombosis & diathesis haemorrhagica. Supplementum. 1969; 21: 129 (#J0013916) |
| 87. | Johnson AJ; Karpatkin MH; Newman J. "Preparation of and clinical experience with antihemophilic factor concentrates". Thrombosis & diathesis haemorrhagica. Supplementum. 1968; 35: 49 (#J0035236) |
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